--- title: "Comfort Inn & Suites Sikeston I-55, Sikeston, MO" description: "Comfort Inn & Suites Sikeston I-55 in Sikeston, MO: Enjoy a comfortable stay at the Comfort Inn & Suites Sikeston I-55, conveniently located within a 10-minute walk of The Book Bug and the City of Miner Convention Center. Our hotel offers an indoor pool and fitness center, perfect…" canonical: https://nowah.xyz/stays/united-states/sikeston-mo/hotels/comfort-inn-and-suites-sikeston-i-55-c1e93d8da44a --- # Comfort Inn & Suites Sikeston I-55, Sikeston, MO Comfort Inn & Suites Sikeston I-55 in Sikeston, MO: Enjoy a comfortable stay at the Comfort Inn & Suites Sikeston I-55, conveniently located within a 10-minute walk of The Book Bug and the City of Miner Convention Center. Our hotel offers an indoor pool and fitness center, perfect… ## About Comfort Inn & Suites Sikeston I-55 Enjoy a comfortable stay at the Comfort Inn & Suites Sikeston I-55, conveniently located within a 10-minute walk of The Book Bug and the City of Miner Convention Center. Our hotel offers an indoor pool and fitness center, perfect for unwinding after a day of exploring. Stay connected with complimentary Wi-Fi in our 64 air-conditioned guest rooms, each equipped with a coffee/tea maker and a private bathroom. Additional amenities include a business center, 24-hour front desk service, and laundry facilities. Free self-parking is available on-site. Nearby attractions include the Sikeston Depot Museum (3. 3 mi) and the Mississippi River (17. 6 mi). We are also a short drive from the Cape Girardeau Municipal Airport (CGI). ## Location 109 Matthews Lane Sikeston, MO, United States Coordinates: 36.89044168595757, -89.53585647807813 Hotel classification: 3 stars. This is not a guest review score. ## Facilities - Wi-fi — Facilities - 24-hour reception — Facilities - Indoor freshwater pool (extra charge) — Entertainment - Car park — Facilities - Fitness — Sports - Gym — Facilities - Laundry service — Facilities - Wheelchair-accessible — Facilities - Breakfast — Meals - Business centre — Business - Continental breakfast — Meals - Hot tub — Health - Lift access — Facilities - Meeting room — Business - Small pets allowed (under 5 kg) — Facilities ## Room options ### DOUBLE Accessible-Two Queen Beds Up to 4 guests. ### SUITE NON SMOKING Up to 8 guests. ### QUADRUPLE Accessible-Queen Size Bed Up to 6 guests. ### DOUBLE Accessible Up to 4 guests. ### SUITE KING SIZE BED Up to 8 guests. ### DOUBLE KING SIZE BED Up to 4 guests. ### QUADRUPLE QUEEN BED NON SMOKING Up to 6 guests. ### DOUBLE Accessible KING SIZE BED Up to 2 guests. 1 × King-size bed 150-183 width Wake-up service; Satellite TV; Cable TV; Hairdryer; Fridge; Microwave; Tea and coffee making facilities; Wheelchair-accessible ## Property photos - [Comfort Inn & Suites Sikeston I-55, photo 1](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_016.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 2](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_017.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 3](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_019.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 4](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_014.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 5](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_012.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 6](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_013.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 7](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_023_20250727_221538.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 8](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_024_20250727_221539.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 9](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_ro_025_20250727_221540.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 10](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_p_062_20251231_182722.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 11](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_p_063_20251231_182726.jpg) - [Comfort Inn & Suites Sikeston I-55, photo 12](https://photos.hotelbeds.com/giata/bigger/22/225061/225061a_hb_f_008_20251231_182741.jpg) ## Before you confirm Room configuration, meals, cancellation terms, prices and availability are checked with your selected offer in Nowah. [Find a stay with Nowah](https://app.nowah.xyz/)