--- title: "Holiday Inn Express and Suites St.Louis South-I-55, St. Louis, MO" description: "Holiday Inn Express and Suites St.Louis South-I-55 in St. Louis, MO: Welcome to the new Holiday Inn Express & Suites St. Louis South I-55! South St. Louis's newest and most modern Holiday Inn Express hotel is nestled within a growing development at the intersection of Butler Hill Road and I-55…" canonical: https://nowah.xyz/stays/united-states/st-louis-mo/hotels/holiday-inn-express-and-suites-st-louis-south-i-55-e7c9ec8ecf4f --- # Holiday Inn Express and Suites St.Louis South-I-55, St. Louis, MO Holiday Inn Express and Suites St.Louis South-I-55 in St. Louis, MO: Welcome to the new Holiday Inn Express & Suites St. Louis South I-55! South St. Louis's newest and most modern Holiday Inn Express hotel is nestled within a growing development at the intersection of Butler Hill Road and I-55… ## About Holiday Inn Express and Suites St.Louis South-I-55 Welcome to the new Holiday Inn Express & Suites St. Louis South I-55! South St. Louis's newest and most modern Holiday Inn Express hotel is nestled within a growing development at the intersection of Butler Hill Road and I-55, just one mile south of I-270/255, with access to everything St. Louis offers. Located just 14 miles south of downtown St. Louis at exit 195 off I-55, business travelers will benefit from our central location with easy on/off access to I-55, connecting to different areas of St. Louis within minutes. The hotel complex includes the Barnes-Jewish Siteman Cancer Center and Mercy Health. We are also minutes from MetLife, Anheuser-Busch, Cigna, and the National Cemetery Administration. Our non-smoking Holiday Inn Express & Suites St. Louis I-55 hotel offers convenient access for guests visiting Busch Stadium, the Gateway Arch, Grant's Farm, the Magic House, the St. Louis Science Center, the St. Louis Zoo, Forest Park, River City Casino, and much more! Hotel guests can enjoy an array of amenities, including suites, an indoor pool, a Suite Shop, two meeting rooms, a complimentary Express Start breakfast, complimentary high-speed wired and wireless internet, a comfortable Great Room with an outdoor patio, and warm cookies and milk served nightly. Experience genuine Midwestern hospitality at our South St. Louis location. ## Location 4250 Midamerica Lane St. Louis, MO, United States Coordinates: 38.485568, -90.353927 Hotel classification: 3 stars. This is not a guest review score. ## Facilities - Wi-fi — Facilities - 24-hour reception — Facilities - Indoor freshwater pool — Entertainment - Car park (extra charge) — Facilities - Fitness (extra charge) — Sports - Launderette (extra charge) — Facilities - Laundry service (extra charge) — Facilities - Wheelchair-accessible — Facilities - Babysitting service (extra charge) — Facilities - Bar (extra charge) — Catering - Bellboy service (extra charge) — Facilities - Breakfast — Meals - Business centre (extra charge) — Business - Casino (extra charge) — Entertainment - Fax (extra charge) — Business - Golf (extra charge) — Sports - Lift access (extra charge) — Facilities - Meeting room — Business - Printer (extra charge) — Business - Shop (extra charge) — Facilities - Smoking area (extra charge) — Catering - Tennis (extra charge) — Sports ## Room options ### SUITE ONE BEDROOM Accessible Up to 8 guests. ### DOUBLE KING SIZE BED Up to 4 guests. 1 × King-size bed 150-183 width Wheelchair-accessible; Wi-fi ### DOUBLE DELUXE KING BED Up to 4 guests. ### Room STANDARD Up to 10 guests. ### DOUBLE TWO QUEEN BEDS Up to 4 guests. 2 × Queen-size bed 150-154 width Wi-fi; Wheelchair-accessible ### QUADRUPLE TWO QUEEN BEDS NON SMOKING Up to 6 guests. ### SUITE TWO QUEEN BEDS ONE BEDROOM Up to 6 guests. 2 × Queen-size bed 150-154 width Wi-fi; Wheelchair-accessible ### SUITE Accessible KING SIZE BED Up to 4 guests. 1 × King-size bed 150-183 width Wi-fi; Wheelchair-accessible ## Property photos - [Holiday Inn Express and Suites St.Louis South-I-55, photo 1](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_025.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 2](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_036.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 3](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_037.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 4](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_060.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 5](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_072.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 6](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_028.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 7](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_073.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 8](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_074.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 9](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_075.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 10](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_076.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 11](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_077.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 12](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_049.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 13](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_026.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 14](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_027.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 15](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_078_20250610_155918.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 16](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_080_20250610_155923.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 17](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_081_20250610_155926.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 18](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_082_20250610_155928.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 19](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_083_20250610_155931.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 20](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_084_20250610_155933.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 21](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_085_20250610_155936.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 22](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_086_20250610_155938.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 23](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_088_20250610_155943.jpg) - [Holiday Inn Express and Suites St.Louis South-I-55, photo 24](https://photos.hotelbeds.com/giata/bigger/61/615149/615149a_hb_ro_096_20250610_160003.jpg) ## Before you confirm Room configuration, meals, cancellation terms, prices and availability are checked with your selected offer in Nowah. 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